Ginkgo biloba is an ancient tree whose fan-shaped leaves contain flavone glycosides and terpene lactones. It's usually sold as standardized leaf extract (such as EGb-type extracts), calibrated to these marker compounds. Important: ginkgo can interact with blood thinners – always check with a doctor beforehand if you're having surgery or taking medication at the same time. Quality shows in the standardized extract.
Few plants are as unmistakable as the ginkgo: its fan-shaped leaves appear on postcards, in poems, and in parks around the world. Botanically, Ginkgo biloba is a living fossil – the sole surviving species of a plant group that existed long before today's broadleaf and coniferous trees. In this guide, we take a purely factual look at the ginkgo: where the tree comes from, what compounds are found in its leaves, how extracts are made from them, and what to look for regarding quality and use. This is explicitly about botanical and historical context – not health-effect promises.
What Is Ginkgo Biloba? The Tree and Its Leaf
Ginkgo biloba is a deciduous tree that can grow over 30 meters tall and reach a very old age. It originally comes from China, where individual specimens have been tended at temples and in gardens for centuries. Today, the ginkgo grows as a hardy street and park tree in many temperate regions, because it's resistant to exhaust fumes, diseases, and pests.
Characteristic is the fan-shaped leaf, which often has a notch in the middle – hence the species name biloba ("two-lobed"). Ginkgo is dioecious: there are male and female trees. Female specimens produce yellowish seeds that develop an intense smell; for the extraction of leaf extracts, it's mainly the green foliage that plays the central role. Botanically, the ginkgo holds a special position: it can't be clearly classified as either a conifer or a broadleaf tree, and forms its own taxonomic division.
The tree's resilience is remarkable. Ginkgos can live for several hundred years, and in individual cases over a thousand, and they tolerate heat, cold, and air pollutants astonishingly well. That's exactly why they're popular as street and avenue trees. In autumn, the foliage turns a brilliant golden yellow before falling – a trait that makes the tree easy to recognize even from a distance. For raw material extraction, the foliage is typically harvested in summer, when the content of the characteristic compounds is considered especially favorable.
Compounds: Flavone Glycosides and Terpene Lactones
The ginkgo leaf has been well studied chemically. Two groups of compounds are mentioned especially often:
- Flavone glycosides (flavonoids): plant compounds also found in similar form in many other leaves, flowers, and fruits. They shape a large part of the leaf's characteristic compound profile.
- Terpene lactones: a group typical of ginkgo, which includes the so-called ginkgolides and bilobalide, among others. These compounds are comparatively rare in the plant world and are considered a botanical "signature" of the ginkgo.
The leaf also contains other accompanying substances, including ginkgolic acids. During the production of standardized extracts, these are deliberately removed to a large extent, since they're considered undesirable accompanying substances. The total content and the ratio of compounds depend heavily on variety, location, time of harvest, and processing. For this reason, a simple leaf powder can differ significantly from a concentrated, standardized extract – a point that's often overlooked when comparing different products. If you'd like a deeper understanding of why plant compounds can be present differently in the body, our guide Bioavailability explained simply is worth a look.
Traditional Use: Historical and Cultural
The ginkgo looks back on a long cultural history. In its native region of East Asia, the tree was cultivated at temples for centuries and is regarded in many places as a symbol of longevity and permanence. In European cultural history, it was immortalized in literature, among other things – Johann Wolfgang von Goethe dedicated a well-known poem to the ginkgo leaf, taking up the split leaf as a motif.
This context is deliberately meant to be purely historical and cultural. No health claim for a dietary supplement can be derived from traditional use handed down through history. Historical use describes what people did in the past – it's not evidence of a specific effect and doesn't replace scientific evaluation.
Forms & Standardization: From Leaf to Extract
Ginkgo is offered in very different forms. Broadly, they can be categorized as follows:
- Dried leaf / tea: the simplest form, with a compound content that fluctuates greatly and is hard to control.
- Powder from ground leaf: also only lightly standardized; the content depends directly on the raw material.
- Standardized dry extract: the most tightly controlled form. Here, a concentrate is obtained from many leaves and adjusted to defined marker compounds.
With standardized extracts, you frequently come across the designation EGb followed by a number (such as EGb 761). Such abbreviations denote specified, elaborately processed leaf extracts that are adjusted to fixed levels of flavone glycosides and terpene lactones and are greatly reduced in ginkgolic acids. An important point for context: in Europe, such standardized ginkgo leaf extracts are primarily known as registered or approved herbal medicinal products. Different legal frameworks apply to a dietary supplement – more on that below.
The term standardization means a manufacturer keeps the content of certain marker compounds as consistent as possible from batch to batch. This creates comparability, but on its own says nothing about a health benefit. If you'd like to understand how individual plant extracts fit into an overall approach, you'll find suggestions in our guide Combining supplements the right way.
Quality: What to Look For
With botanical extracts, the quality of the raw material and processing determines the final product. Useful points of reference include:
- Clear labeling: which part of the plant (leaf) is used, in what form (extract, powder), and in what ratio? A transparent label makes comparison easier.
- Marker compound information: for extracts, figures on flavone glycosides and terpene lactones help you assess products.
- Reduced ginkgolic acids: high-quality leaf extracts are processed so that the ginkgolic acid content is kept low.
- Origin and testing: information on raw material origin and lab analyses builds trust. We explain what seals and analyses actually mean in Lab-tested – what does that mean?.
It's also worth looking beyond ginkgo: many questions about processing, content, and purity arise in a very similar way with other plant extracts. How concentration and absorption of a substance can differ is explained in our guide Bioavailability explained simply.
Use: General Guidance
As a general rule for dietary supplements: stick to the intake recommendation on the packaging and don't exceed the stated amount. Dietary supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. Depending on the form, ginkgo products are offered as capsules, tablets, drops, or tea; practical handling depends on the specific product. Capsules and tablets have the advantage of a fixed, easily dosed amount, while the content of loose leaf or tea is hardly possible to determine precisely. Store products dry, protected from light, and out of the reach of children, and pay attention to the best-before date.
If you want to combine several products, get an overview beforehand so that amounts don't unintentionally add up. We've summarized the basic principles for this in Combining supplements the right way.
Honestly Assessed – and Safety
Honesty requires a clear legal picture: in Europe, ginkgo is primarily established as a registered or approved herbal medicinal product. For use as a dietary supplement, on the other hand, there are no approved health claims. In concrete terms, that means ginkgo, as a dietary supplement, must not and cannot be marketed with claims about memory, concentration, circulation, or similar effects. This guide deliberately makes no such claims – it limits itself to botany, compounds, and neutral context.
Safety and interactions – please read carefully:
- Blood-thinning medications: ginkgo can interact with anticoagulant or blood-thinning drugs (such as those from the group of anticoagulants or platelet inhibitors). Anyone taking such medication should not use ginkgo without prior medical clearance.
- Before surgery: ahead of planned surgical procedures, this topic must be discussed with the treating physicians; it's often advised to stop such products in good time beforehand.
- Pregnancy and breastfeeding: during these life stages, intake should generally be discussed with a doctor beforehand.
- Other medications and pre-existing conditions: if you're taking other medication or have underlying conditions, it's generally advisable to consult a doctor or pharmacist.
This information does not replace individual advice. If you're unsure, medical or pharmacist guidance is always the right first port of call.
Bottom line: the ginkgo is a botanically fascinating tree with an unmistakable leaf and a long cultural history. Its leaves contain characteristic compounds such as flavone glycosides and terpene lactones, which can be concentrated in standardized extracts. Anyone looking into ginkgo should keep an eye on origin, form, and labeling – and take the notes on interactions seriously. As a dietary supplement, this overview remains deliberately informational, without health-effect promises.
Health notice: This guide is for general information purposes only and does not replace individual medical or pharmaceutical advice. Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. If you have health concerns, are pregnant or breastfeeding, or are taking medication, please consult a doctor or pharmacist. How our guides are created →
Sources
- Final European Union herbal monograph on Ginkgo biloba L., folium — European Medicines Agency (EMA), Committee on Herbal Medicinal Products (HMPC), 2015
- Ginkgo – Information on Herbal Extracts and Dietary Supplements — Verbraucherzentrale, 2024
- Ginkgo — National Center for Complementary and Integrative Health (NCCIH), 2020
- List of Commission E Monographs (Phytotherapy) Published in the Federal Gazette (Bundesanzeiger) — German Federal Institute for Drugs and Medical Devices (BfArM), 1994








