Several nutrients, under an approved EU health claim, “contribute to the reduction of tiredness and fatigue”: iron, magnesium, vitamin C, folate, and the B vitamins B2, B3, B5, B6, and B12. The effect is most noticeable when there's an existing shortfall. A blood test can clarify this beforehand; persistent exhaustion should be checked out by a doctor.
You're actually getting enough sleep, and yet you feel foggy-headed in the morning, and by the afternoon your head is practically hitting the keyboard? Tiredness and exhaustion are among the most common reasons people start thinking about their nutrient intake in the first place. The good news: this topic area has an unusually solid evidence base. Several nutrients at once, according to verified EU claims, "contribute to the reduction of tiredness and fatigue" – that's not a marketing slogan, it's an official health claim.
In short: iron, magnesium, vitamin C, folate and several B vitamins (B2, B3, B5, B6, B12) carry the authorised claim "contributes to the reduction of tiredness and fatigue". They work most noticeably where there's an actual shortfall. A blood test – especially for iron – brings clarity beforehand. Persistent, pronounced exhaustion should be checked out by a doctor.
The essentials at a glance
- Several nutrients carry the claim "contributes to the reduction of tiredness and fatigue": including iron, vitamin C, B2, B3, B5, B6, B12, folate and magnesium.
- Iron and B12 are especially relevant because their supply can become critical with certain diets.
- A blood test brings clarity before you supplement in a targeted way – especially for iron.
- Sleep, exercise, fluids and meal rhythm are the real foundation.
- Important: Always have persistent, pronounced exhaustion checked out by a doctor.
Why nutrients can make you tired in the first place – the mechanism
At its core, tiredness is often an energy problem at the cellular level. Every one of your cells generates energy in its power plants, the mitochondria, producing the universal energy carrier ATP. This process is a long chain of chemical reactions – and vitamins and minerals hang off many links of that chain as cofactors. Iron transports the oxygen without which the power plants can't run. B vitamins act like spark plugs in energy metabolism. Magnesium stabilises the ATP molecule itself. If a building block is missing, energy output drops – and you feel that as tiredness and fatigue. That's exactly why the "anti-fatigue" claim is authorised for these nutrients.
The nutrients with an "anti-fatigue" claim
What makes this topic area so special: the claim "reduction of tiredness and fatigue" is authorised for several nutrients at once. So you can rely on it with confidence – in the correct wording:
| Nutrient | Contributes to… |
|---|---|
| Iron | reduction of tiredness; normal energy metabolism; normal oxygen transport |
| Vitamin B12 | reduction of tiredness; normal energy metabolism; nervous system |
| Vitamin B6 | reduction of tiredness; normal energy metabolism |
| Vitamin C | reduction of tiredness; normal energy metabolism |
| Folate | reduction of tiredness; normal blood formation |
| Riboflavin (B2), niacin (B3), pantothenic acid (B5) | reduction of tiredness; normal energy metabolism |
| Magnesium | reduction of tiredness; normal energy metabolism; nervous system |
Iron: the classic nutrient for tiredness
Iron is central to oxygen transport in the blood and to energy metabolism. Inadequate iron intake is one of the most common nutritional gaps worldwide – especially among menstruating women, vegetarians and vegans. But be careful: please don't take iron on a hunch and on an ongoing basis. Too high an iron status isn't desirable, and the body has hardly any way to get rid of excess iron again. The right approach is a blood test (ferritin) at the doctor's. More depth: Recognising and Preventing Iron Deficiency and How Long Does It Take for Iron to Work?.
Vitamin B12: important for plant-based diets
Vitamin B12 occurs practically only in animal foods. Anyone eating a vegan diet should therefore supplement B12 in a targeted way – here, supplementation isn't optional but recommended. B12 contributes to normal energy metabolism, to normal function of the nervous system and to the reduction of tiredness. More on this in Covering Vitamin B12 on a Vegan Diet and Vitamin B12 Deficiency: Signs.
What research is investigating
The role of these nutrients in energy metabolism is established, textbook knowledge in nutritional science. Less clear-cut – and therefore worth stating honestly – is the question of whether additional intake still "adds" anything when supply is already good. The answer is usually: nutrients help where there's an actual gap. Anyone who is already well supplied generally doesn't notice a benefit from extra capsules. Coenzyme Q10, as a building block of energy production, is also being studied in this context – but the evidence base and authorisation mainly apply to the vitamins and minerals named above. That's why the blood test is so useful: it shows where supplementing is genuinely worthwhile.
Measure first, then supplement – why that saves so much
Perhaps the most important practical tip for tiredness is: don't guess, measure. A simple blood panel with values such as ferritin (iron stores), vitamin B12 and, depending on the situation, further parameters shows where a gap actually exists. That saves you two things: unnecessary supplements that don't help anyway when supply is good, and the risk of overlooking precisely the nutrient that's actually missing. Especially with exhaustion, which has so many possible causes, this targeted view is worth its weight in gold – and it turns a vague "I'll just take something" into a well-founded decision.
In practice: combining and taking them correctly
A few small habits increase the benefit. Iron from plant sources is absorbed considerably better when combined with vitamin C – a bit of bell pepper or a glass of orange juice with a lentil dish makes a difference. Coffee and black tea, on the other hand, inhibit iron absorption, which is why it's better to drink them with some distance from meals. B vitamins are often taken in the morning, since they support energy metabolism. And because overall supply is what matters with tiredness, a deliberate look at timing and combinations makes more sense than simply taking "more".
Magnesium, B vitamins and vitamin C: the trio in energy metabolism
Besides iron and B12, three further building blocks deserve a look. Magnesium is involved in over 300 enzymatic reactions, many of them in energy metabolism – especially during stressful periods or with a lot of exercise, requirements can play a role. The B vitamins (B2, B3, B5, B6 and B12) are the classic "engine oil" of energy metabolism and work closely together, which is why a B-complex is often practical. And vitamin C not only contributes to normal energy metabolism and the reduction of tiredness, but also improves the absorption of plant-based iron on the side – a double benefit you can combine cleverly.
Typical situations where tiredness becomes an issue
- Menstruating women: Regular blood loss increases iron requirements – iron is the most common nutritional gap here. More depth: Iron Requirements in Women.
- People eating vegan or vegetarian: B12 must be supplemented with a vegan diet, and plant-based iron is absorbed less well – vitamin C alongside it helps.
- Lots of exercise, lots of sweating: Minerals are lost through sweat; magnesium is then a useful building block.
- Stressful phases of life: Irregular meals and sleep often take a bigger toll on energy than any single nutrient.
The foundation doesn't come in capsule form
Before reaching for supplements, it's worth taking an honest look at the basics – they often matter most:
- Sleep: amount and regularity – see Sleep Better Naturally.
- Fluids: even mild dehydration can cause tiredness – Nutrients for Fluid Balance.
- Energy metabolism: an overview of the nutrients involved is under Nutrients for Energy Metabolism.
- Springtime: seasonal tiredness? See Spring Fatigue & Nutrients.
Honestly assessed
What's established: the nutrients named contribute to the reduction of tiredness and to normal energy metabolism – most noticeably where there's an actual shortfall. What cannot be claimed is that a supplement turns tiredness into energy the way an energy drink does, or "fixes" chronic exhaustion. Persistent, pronounced or suddenly occurring exhaustion should be checked out by a doctor – there can be underlying causes that a capsule doesn't address.
Suitable products from Scheunengut
For targeted basic supply, you'll find Iron, B Vitamins, Magnesium and the topic world Energy with us. You can go deeper into the topic in Energy: Magnesium, Iron & B Vitamins, Recognising & Preventing Iron Deficiency, Vitamin B12 Deficiency: Signs and Nutrients for Energy Metabolism. All products are lab-tested and made in Germany. Especially with iron: check the blood value first, then supplement in a targeted way.
Frequently asked questions (FAQ)
Which nutrients are proven to help against tiredness?
The authorised claim "contributes to the reduction of tiredness and fatigue" applies to iron, magnesium, vitamin C, folate and several B vitamins (B2, B3, B5, B6, B12). They work most noticeably where there's an actual shortfall. Anyone who is already well supplied generally doesn't notice a benefit from extra capsules.
Should you take iron just on suspicion?
No. Iron shouldn't be taken on a hunch and on an ongoing basis, because too high an iron status isn't desirable and the body can barely excrete excess iron. The right approach is a blood test (ferritin) at the doctor's. That way you can supplement in a targeted, safe manner if a deficiency actually exists.
Why is vitamin B12 so important on a vegan diet?
Vitamin B12 occurs practically only in animal foods. With a purely plant-based diet, targeted supplementation is therefore not optional but recommended. B12 contributes to normal energy metabolism, to the function of the nervous system and to the reduction of tiredness – a deficiency can show up as exhaustion, among other things.
When should tiredness be checked out by a doctor?
If exhaustion is persistent, pronounced or has appeared suddenly, it should be checked out by a doctor. There can be underlying causes that a supplement doesn't address. Nutrients support energy metabolism but are no substitute for a diagnosis in the case of longer-standing or severe complaints.
Health notice: This guide is for general information purposes only and does not replace individual medical or pharmaceutical advice. Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. If you have health concerns, are pregnant or breastfeeding, or are taking medication, please consult a doctor or pharmacist. How our guides are created →
Sources
- Reference Values — German Nutrition Society (DGE)
- Vitamin D – Reference Value — German Nutrition Society (DGE)
- Updated Proposed Maximum Levels for Vitamins and Minerals in Food Supplements and Fortified Foods (Opinion 006/2024) — German Federal Institute for Risk Assessment (BfR), 2024
- Maximum Levels for Vitamins and Minerals in Food Supplements and Fortified Foods (Press Release) — German Federal Institute for Risk Assessment (BfR), 2021
- When Will There Finally Be Maximum Levels for Vitamins and Minerals? — Verbraucherzentrale








