Supplement Guide for Biohackers: Spermidine, Lions Mane & Q10

Biohackers think in systems: sleep, regeneration, cognitive performance and cellular health are measured, optimised and readjusted again and again. Anyone who treats their body like a project looks for raw materials with a clear composition, transparent dosing and traceable quality – no marketing fog, but substance that can be proven on the label. Instead of a single miracle cure, it is about a well-considered stack in which every building block has a task and is tested individually. In this guide, we show you what matters for the goal of self-optimisation, why standardisation is more important than any promise and which products from our range fit into a methodical, honest routine.

An honest note up front: no raw material in the world compensates for poor sleep, chronic stress or a diet of convenience products. The most exciting effects in biohacking almost always arise where someone first tidies up their fundamentals and then refines in a targeted way. We therefore deliberately treat supplements as what they are – a tool in the kit, not the shortcut. If you share this standard, you will find in the following products transparently declared raw materials with which you can experiment cleanly, instead of falling for flowery marketing promises.

What matters for the goal of biohackers & optimisers

Biohacking is rarely about a single active ingredient, but about the interplay and about repeatability. What is decisive is well-characterised raw materials: standardised extracts with a stated active ingredient content, clearly declared amounts and tested purity. That is exactly how you recognise serious products – and we stay strictly with what is officially permissible in our statements, because anyone who wants to optimise does not want empty promises.

Spermidine is a natural polyamine compound that occurs in many foods such as wheat germ, matured cheese and pulses. In the biohacker scene, spermidine is one of the most discussed topics around cellular processes. Since it is a plant-based natural substance and not a nutrient with an authorised claim, we describe it in terms of its origin and composition: standardised wheat germ extract with a defined spermidine and polyamine content.

Hericium erinaceus (Lions Mane) is an edible and medicinal mushroom traditionally used in East Asia. For our purposes, what counts above all is the standardised quality: 30 % polysaccharides and 5 % beta-glucan in the extract are robust key figures. We make statements about mushrooms exclusively in terms of traditional use and transparent composition, never about medicinal effects.

Coenzyme Q10 (ubiquinone) is a substance produced by the body from the mitochondria, the power plants of the cells. For optimisers who pay attention to cellular energy production, it is a frequently chosen building block. There is no authorised health claim for Q10, so our description deliberately stays factual and is limited to origin and content.

A good stack also thrives on sequence. Instead of starting five raw materials in parallel straight away, you introduce them individually and staggered over time – this way each effect can be cleanly attributed. Pay attention to tolerability, the time of intake and the combination with or without a meal, because some extracts are absorbed better with fatty food. Additionally document objective markers accessible to you, such as your sleep data or your training performance. This methodical approach distinguishes real biohacking from mere capsule counting and protects you from spending money on raw materials that do nothing for you personally.

A further point concerns the quality of the raw materials themselves. Between a genuine extract standardised to an active ingredient and simply ground starting material lie worlds – even if both may sound similar on the label. Pay attention therefore to details such as the percentage beta-glucan content in medicinal mushrooms, the polyamine proportion in wheat germ extract or the extract ratio. Just as relevant are origin and place of manufacture: raw materials from German or European production are subject to strict controls. Anyone who makes these criteria a habit when buying already filters out a large part of the overpriced or under-dosed products on the market in advance and invests their budget where there is actually substance.

Our product recommendations

Spermidine from wheat germ extract

100 % natural wheat germ extract with 3 mg of spermidine per capsule and a 5 % polyamine content – standardised and transparently declared, so you know exactly what is in every capsule. For biohackers who value a defined, plant-based raw material rather than opaque mixtures. With 120 capsules per tin, a plannable, long-term routine can be built up in which you can control the intake precisely.

View Spermidine

Lions Mane (Hericium erinaceus)

A highly concentrated extract with 1300 mg per dose, standardised to 30 % polysaccharides and 5 % beta-glucan, manufactured in Germany. The lion's mane mushroom has been used traditionally in East Asia for centuries and is one of the most popular medicinal mushrooms in modern biohacking stacks. Standardisation to beta-glucan is the decisive quality feature here – it distinguishes a genuine extract from mere mushroom powder. 180 capsules ensure sustained intake over weeks.

View Lions Mane

Coenzyme Q10 (ubiquinone)

High-dosed ubiquinone from plant-based fermentation – free of animal raw materials. Coenzyme Q10 sits naturally in the mitochondria of every cell and is thus a logical candidate for everyone who wants to accompany their system at the cellular level. Clearly dosed, obtained purely from plants and easy to integrate into the daily routine, ideally with a fatty meal.

View Coenzyme Q10

Fundamentals first

The best stack is of little use if the basics are missing. For optimisers this means quite concretely: a consistent sleep-wake rhythm, real strength or endurance training, morning sunlight to steer the internal clock, a nutrient-dense diet with sufficient protein and a functioning stress management. These five levers, in experience, move more than any capsule. Only when they are in place do targeted supplements deliver a noticeable additional benefit – before that, you are optimising in the wrong place.

Biohacking thrives on measuring and on discipline: change only one variable at a time if possible, document sleep, energy and focus over several weeks and give every new raw material enough time before you evaluate. This way you recognise what really works for you, instead of relying on anecdotes. Also do not take nutrients twice if products overlap. If you take medication, are pregnant or have pre-existing conditions, please discuss new food supplements with your doctor beforehand.

Also beware of the classic optimiser mistake of constantly changing everything at the same time. Anyone who changes training, nutrition, sleep and three new raw materials in the same week cannot say in the end what had an effect. Patience is a real lever here: give every change time, keep the remaining variables as stable as possible and make decisions on the basis of your own data rather than forum hype. This way, over the months, you build yourself a routine that demonstrably works for your body – and not only sounds good on paper.

Finally, do not underestimate the role of regeneration. Many optimisers constantly chase new stimuli – colder showers, harder fasting, more raw materials – and forget that adaptation happens in recovery, not in stress. Therefore deliberately plan phases in which you add nothing new, but simply implement the proven consistently and let your body come to rest. These deload phases in the broader sense prevent you from chronically overexerting yourself, and often make the actual progress visible in the first place. Optimisation is a marathon of consistent habits, not a sprint of ever new hacks.

Frequently Asked Questions (FAQ)

What makes a good biohacking raw material?

Standardisation and transparency: a stated active ingredient content such as percent beta-glucan or milligrams of spermidine per capsule, clear amount specifications and traceable origin. You find exactly these details with our products – they allow you to control doses precisely and to attribute results at all.

Can I combine spermidine, Lions Mane and Q10?

These three raw materials address different areas and can in principle be brought together in one routine. From a methodical point of view, however, it is wiser to start with one product each, in order to be able to assess tolerability and effect separately before you stack them.

How long should I test a raw material?

Plan at least four to eight weeks of continuous intake. Natural substances and standardised extracts rarely unfold their benefit from one day to the next, but over time. Too short a test almost always leads to wrong conclusions in both directions.

Are plant-based raw materials superior to synthetic ones?

Not automatically – what is decisive is purity, standardisation and the actual dose, not the origin alone. Many biohackers prefer plant-based sources such as wheat germ extract for reasons of origin, tolerability and traceability.

At what time of day do I take the products?

That depends on the raw material and your personal routine. Many take medicinal mushrooms and Q10 in the morning with a meal, because that fits well into the day. In any case, stick to the dosage recommendation on the pack.